Preimplantation Genetic Diagnostics (PGD)
Preimplantation Genetic Diagnostics (PGD) is a range of methods for the detection of hereditary diseases in the embryo before the embryo transfer into the uterus. The name of the method bears some hidden advertising or even a guarantee. In fact, the exact name of the method is "Pre Embryo Transfer Genetic Diagnostics" (PET-GD).
It should be noted that no implantation as a guarantee after using this method is implied. So, this should be explained. The only point is that we use all genetic methods for the diagnostics of genetic characteristics of the embryo only with the purpose of transferring genetically healthy material to the uterus.
Indeed, because of PGD, couples with a high risk of transmitting various inherited genetic diseases have an opportunity to give birth to a healthy child or healthy children.
PGD is necessary for all couples where genetic abnormalities were identified in the husband or the wife.
If a chromosome abnormality was found in the karyotype, a chromosomal profile, of the wife or the husband.
If a woman has had at least two spontaneous abortions.
If a woman has had at least one case of missed abortion due to a confirmed chromosomal abnormality (karyotyping of the embryo or chorionic villi in missed abortion).
If a woman has had at least one case of missed abortion due to structural abnormalities of the embryo identified by ULTRASOUND SCANNING or EMBRYOSCOPY.
If a couple has had several failures of IVF protocols: no pregnancy, biochemical pregnancy, missed abortion, miscarriage.In women undergoing IVF protocols at the age of 35 to 42.
In couples diagnosed with sex-linked genetic diseases, such as hemophilia. The birth of a girl would release the family from suffering.
Finally, THE BIRTH OF AN HEIR.
Or the birth of A GIRL, a welcome delight for the mother's heart in a family full of boys/men.
1. Determination of the karyotype of the patient
2. Determination of the karyotype of amniocytes from the ongoing
3. Determination of the karyotype of chorionic villi in the abortive
4. Determination of the karyotype of chorionic villi from the ongoing
5. Determination of the karyotype of chorionic villi from the ongoing
pregnancy, FISH method
6. Determination of the karyotype of amniocytes from the ongoing
pregnancy, FISH method
7. FISH assay of blood lymphocytes (1 chromosome)
8. FISH assay of blood lymphocytes (2 chromosomes)
9. Semen analysis, FISH method
10. Semen analysis, FISH method for investigation of individual
11. Immunization with husband's lymphocytes
12. Irrigation of the uterine cavity with autologous peripheral blood
13. Irrigation of the uterine cavity with peripheral blood platelets
14. Preimplantation genetic diagnostics (PGD, 5 chromosomes)
15. Preimplantation genetic diagnostics (PGD, 7 chromosomes)
16. Preimplantation genetic diagnostics of all chromosomes or by