IVF STAGES (VIDEO)
The most important stage in IVF is the establishment of a correct diagnosis. Only a correct diagnosis allows conducting successful treatment. It should be emphasized that we settle upon inexplicability of causes of fertility disorders in up to 15% of the cases. In more than 70% of the cases, we register complex fertility disorders.
CHOICE OF THE PROTOCOL
The gold standard of protocols is the long mid-luteal protocol. In the vast majority of cases, we follow this protocol. In fact, our experience encompasses a wide range of choices of treatment protocols, which we do in each individual case.
INITIATION OF THE PROTOCOL
Usually, the initiation of the protocol falls into the middle of the luteal phase. Sometimes, if a cyst formation is registered, we initiate the protocol from the first day of the cycle, although it can be initiated immediately after ovulation.
STIMULATION OF THE FOLLICLE GROWTH
We always handle each case individually. Our experience encompasses the whole range of gonadotropins known and marketed in the world.
Following the latest trends, and to obtain maximum effective results, we use highly purified urinary gonadotropins in most cases in our practice, although all the medicinal products distributed in the country are available.
Protocols of controlled ovarian hyperstimulation (COH) are very diverse. Choice of the protocol depends on various causes, and the course of stimulation depends on a specific ovarian response to COH.
WHEN ARE CHORION GONADOTROPINS ADMINISTERED DURING THE IVF PROGRAM?
Chorion gonadotropins are administered if ultrasonographic signs of the follicle maturity, a diameter of 16 mm, are observed.
Egg retrieval in cycles of controlled ovarian hyperstimulation (COH) and ovulation induction is technically no different from the procedure in
spontaneous cycles. In fact, controlled hyperstimulation is carried out to obtain more oocytes for the purposes of IVF. The first oocyte aspiration in the history was performed under laparoscopic control. With the evolvement of ultrasound techniques, a standard method of oocyte aspiration under ultrasound control was developed. At first, aspiration was performed via a transabdominal access with the full bladder, so the needle passed through the walls of the bladder and its contents. With the development of the transvaginal ultrasound technique, aspiration is performed via a transvaginal access through the lateral fornices of the vagina.
Technical requirements for oocyte aspiration are as follows: the needle should be of a suitable gauge, with the inner diameter of about 1 mm, which allows performing a puncture, on the one hand, with a low probability of an injury of parametrial vessels, and on the other hand, with a low probability of damaging the oocytes. The most important requirement for oocyte aspiration is a strict preclusion of oocyte contact with any toxic substances. The needle is connected with a device for collection of follicular fluid into special test tubes made of plastic with minimum cytotoxic properties. Negative pressure is created by an automatic pump or a 20-mL syringe attached.
Oocyte aspiration with a syringe, with the exception of some inconveniences (frequent changes of syringes during aspiration), has a number of obvious advantages: the possibility of irrigation of the follicle cavity for more thorough aspiration, especially if there are only a few mature follicles or if the IVF program is performed in the spontaneous cycle.
THE EMBRYOLOGICAL STAGE OF THE IVF CYCLE
This is the most important stage of assistance for couples while addressing the problems of infertility. We have paid maximum attention to our embryological part. Unique equipment and techniques allow us to achieve success in the maximum possible number of cases.
We are proud of our embryological capacities. It is our life.
Here is a photograph of an ideal embryo after a unique enzymatic treatment
Embryo transfer is one of the most important stages of IVF, as this stage might be fatal for all the efforts in achieving pregnancy. And it does not matter here what microscope, incubator, or media you have in the laboratory.
Our exclusive experience allows us to neutralize all risks of this stage of IVF.
FREEZING EMBRYOS REMAINING AFTER THE PROGRAM
We pay huge attention to IVF programs and therefore have all the possibilities for cryopreservation of the remaining embryos. It is now the cornerstone of IVF programs.
We have possibilities to guarantee the best outcomes of thawed embryo transfer programs.